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Soo Park, MD
Soo Park, MD
Posted: Monday, April 14, 2025
In a study of prognostic factors affecting patients with cutaneous melanoma that was conducted across 59 countries, women seemed to display more favorable prognostic factors than men as well as higher survival rates with these variables. These findings, which appear to be consistent with previous studies of prognostic factors for patients with cutaneous melanoma, are from the phase III CONCORD-3 study, which was published in the European Journal of Cancer. Claudia Allemani, PhD, of the London School of Hygiene and Tropical Medicine in London, United Kingdom, and colleagues noted that public health efforts aimed at reducing mortality from cutaneous melanoma should be focused on education of early signs of melanoma, particularly in the elderly population in South and East Europe.
The study examined differences in patients’ age, gender, stage at diagnosis, anatomic location of their skin cancer, and country that affected survival outcomes. Data from patients diagnosed between 2000 and 2014 were collected from 284 cancer registries in 59 countries.
The 5-year net survival rates were generally higher among women than men regardless of region, anatomic site, and disease stage. Survival rates at 5 years ranged from 43% to 92% for men and 54% to 95% for women across all countries between 2010 and 2014, as survival rates increased over time for most countries.
Generally, men were older at the time of diagnosis and had a higher rate of metastatic disease than women. The most common anatomic site for the melanoma was the truck in men and the lower limbs and hips in women.
Disclosure: The study authors reported no conflicts of interest.
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