Managing Pediatric Papillary Thyroid Carcinoma: Case Report
Posted: Friday, April 2, 2021
The use of fine-needle aspiration in the early identification of papillary thyroid carcinoma in children with neck masses may improve management strategies, according to the findings published in Case Reports in Endocrinology. Early diagnosis may enable more effective, targeted treatment, which would reduce patient mortality and morbidity, explained Moshawa Calvin Khaba, MD, of the Sefako Makgatho Health Sciences University, South Africa, and colleagues.
The case study featured an 11-year-old girl who presented with a painless, slow-growing lump on the left side of her neck. She had previously received various antibiotics to reduce the size of the mass; however, these strategies were unsuccessful. Physical exam revealed a 50 mm x 40 mm mobile, nontender left neck mass. Complete blood cell count did not reveal any abnormalities in her thyroid function tests. Ultrasonographic analysis was significant for a macrolobulated lesion compressing the left internal jugular vein. Lymph node biopsy was positive for metastatic papillary thyroid carcinoma. A CT scan localized the mass to the inferior pole of the left thyroid lobe, with calcifications and multiple bilateral nodules in the upper lung lobes.
Resection of the thyroid mass revealed a 55 mm x 35 mm x 10 mm hemorrhagic, unencapsulated tumor. Histopathologic analysis confirmed the initial diagnosis of papillary thyroid carcinoma. Furthermore, lymph node clearance was performed and confirmed metastatic papillary metastatic carcinoma. To confirm the efficacy of surgical resection, the patient was administered iodine-131 therapy with prophylactic prednisone. Subsequently, the patient was discharged on daily levothyroxine therapy and was advised to continue lifelong thyroid hormone replacement therapy.
Disclosure: For full disclosures of the study authors, visit hindawi.com.