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Pancreaticoduodenectomy for Metastasized Bladder Cancer: Case Report

By: Kayci Reyer
Posted: Thursday, January 6, 2022

A case study presented in the Annals of Hepato-Biliary-Pancreatic Surgery describes a pancreaticoduodenectomy performed on a man with metastatic bladder cancer. This is believed to be the first report of pancreatectomy for metastasis from bladder cancer. “We believe that curative resection for metastasis to [the] pancreas of urothelial carcinoma might be helpful for its management,” concluded So Jeong Lee, MD, of the Pusan National University School of Medicine in South Korea, and colleagues.

The 61-year-old patient presented with jaundice and and a mass on the pancreas head. He had undergone robot-assisted cystectomy and ileal conduit for high-grade (T3N0 without marginal involvement) bladder cancer 7 months prior. CT imaging identified a 3.6-cm, well-defined pancreatic mass, and MRI confirmed a well-defined mass on the pancreas head, leading to an initial diagnosis of pancreas head cancer. However, the pathologic diagnosis was a 4.9-cm metastatic urothelial carcinoma with lymph node metastasis, based on histologic findings and immunohistochemistry results.

The patient underwent a classic pancreaticoduodenectomy without complication. He was released from the hospital 11 days after the procedure. The surgery was followed by a four-cycle treatment regimen of gemcitabine and cisplatin. At a follow-up of 16 months, the patient had experienced no tumor recurrence.

Disclosure: The study authors reported no conflicts of interest.



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