Thyroid Cancer Coverage from Every Angle
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IGCS 2020: Thyroid Cancer and Pregnancy in Belarus

By: Julia Fiederlein
Posted: Monday, September 21, 2020

In Belarus, thyroid cancer occurs commonly among women of reproductive age. Alexander Shushkevich, MD, of the N.N. Alexandrov National Cancer Center of Belarus, and colleagues conducted a study to evaluate the potential of prolonging pregnancy in patients with thyroid cancer. The results of this prospective case-control study were presented during the digital edition of the 2020 International Gynecologic Cancer Society (IGCS) Annual Global Meeting (Abstract 1261).

Between January 2011 and December 2017, a total of 450 patients were enrolled and divided into three groups: pregnant women with thyroid cancer (group A); patients diagnosed with thyroid cancer (group B); and healthy pregnant women (group C). Both groups A and B included 188 patients. The remaining 74 patients were in group C. Follow-up data for groups A and B were provided for a median of 75 and 60 months, respectively.

In group A, 114 patients were diagnosed with thyroid cancer before pregnancy. A total of 74 patients were diagnosed during pregnancy. According to the investigators, there did not seem to be any significant differences in stage between groups A and B. The majority of patients in groups A and B were diagnosed with stage I thyroid cancer (94.1% and 97.3%, respectively; P > .05). The progression-free survival rate was 94.4% in group A and 97.9% in group B (P > .05). The overall survival rate was the same in both of these groups (100%). In all groups, there appeared to be no significant changes in comparison of pregnancy and childbirth complications.

“Pregnancy and childbirth monitoring, prediction, and correction of revealed complications in patients with thyroid cancer allow to minimize the number of maternal and perinatal complications,” the investigators concluded.

Disclosure: No information regarding conflicts of interest was provided.

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