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AACR COVID-19: Are More Patients With Colorectal Cancer Heading to the ER?

By: Joshua D. Madera, MS
Posted: Thursday, July 23, 2020

The COVID-19 pandemic has led to an increased number of emergency presentations of patients with colorectal cancer, according to a presentation during the 2020 American Association for Cancer Research (AACR) Virtual Meeting on COVID-19 and Cancer (Abstract PO-080). In addition, intestinal perforation was identified as the risk factor of inpatient mortality, according to Mastini Ida Ayu Kade, PhD, of the Moewardi General Hospital, Surakarta, Indonesia, and colleagues.

A total of 26 patients who had colorectal cancer and an emergency presentation were enrolled in the study. All patients were recruited between March and May of 2020. Patients were also tested for COVID-19 using rapid testing. Any comorbidities demonstrated by patients were recorded by the investigators. The study authors assessed inpatient mortality and postoperative complications for these patients.

The study findings revealed that 22 cases were a result of intestinal obstruction, and the remaining 4 cases were a result of diffuse peritonitis due to colonic perforation. All patients were found to be negative for COVID-19 infection. Following exploratory laparotomy, 15 patients were diagnosed with rectal cancer, 10 patients were diagnosed with sigmoid colon cancer, and 6 patients were diagnosed with right-sided colonic cancer. Moreover, patients diagnosed with rectal cancer also demonstrated intestinal perforations.

Treatment of this patient population included tumor resection and primary anastomosis (n = 18) and stoma diversion (n = 8). Furthermore, four inpatients died of perforation. It was later revealed these patients also had cardiopulmonary complications.

Disclosure: No information regarding conflicts of interest was provided.



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