Site Editors

Alexander Drilon, MD

Gregory J. Riely, MD, PhD


Published Medical Literature

Case Series of NTRK-Rearranged Spindle Cell Neoplasms Offers Clinical Insights
Factors to Consider When Developing Laboratory Algorithms for NTRK Fusion Testing
Genetic Abnormalities as Therapeutic Targets in Cholangiocarcinomas
Strategies for Screening Gastrointestinal Stromal Tumors for NTRK Gene Fusions
Testing a Drug in Tumors With Actionable Genetic Biomarkers: Update on Basket Trials
Genomic Landscape of Secretory Breast Carcinomas and NTRK Fusion
NTRK-Rearranged Spindle Cell Neoplasms: New Insights on Histopathology
Employing Aminopyrimidine Derivatives as TRK Inhibitors
Intestinal LMNA::NTRK1-Fused Spindle Cell Neoplasm: Case Report
Working Toward Molecular Actionability in Kinase Fusion–Related Thyroid Carcinomas
ALK Fusion–Positive Neoplasms Can Mimic NTRK-Rearranged Spindle Cell Tumors
Targeted Therapy for NSCLC Based on Genetic Rearrangements
Case Report: NTRK-1–Associated Lipofibromatosis-Like Neural Tumor
Targetable Biomarkers May Be Worth Identifying in Pancreatic and Liver Cancers: Expert Consensus From Spain
Dutch Team Examines the Cost-Effectiveness of Entrectinib in NTRK-Positive Cancer
Spinal Cord Low-Grade Gliomas in Pediatric Patients: Uncovering Rare Genetic Alterations
Educating Patients About Tumor Genomic Testing: Gaps and Opportunities for Improvement
Diagnosing and Treating NTRK Fusion–Positive Tumors: Expert Consensus From China
Role of Tumor Suppressor Gene Count in Predicting the Biology of Translocation-Defined Tumors
Can Molecular Profiling Guide Diagnostic Assessment of Indeterminate Pediatric Thyroid Nodules?
Earlier Use of Larotrectinib in Mismatch Repair–Deficient TRK Fusion–Positive Metastatic Colon Cancer
Case Report: Effect of Larotrectinib Treatment on Infant-Type Hemispheric Glioma With TPR::NTRK1 Fusion
Tropomyosin Receptor Kinases: A Potential Target for Tumors With NTRK Gene Fusions
Case Study of Larotrectinib in Mismatch Repair–Deficient TRK Fusion–Positive Colorectal Cancer
Are NTRK2 Fusions a Targetable Treatment Alternative in Deep-Seated Pediatric Astrocytoma?
Is Pan-TRK Immunohistochemistry Effective in Detecting NTRK Rearrangements in Thyroid Cancer?
High-Grade Glioma With NTRK Fusion Responds to Larotrectinib: Case Report
Frequency and Clinicopathologic Characteristics of NTRK Gene Fusion–Positive Sarcomas
Ongoing Clinical Trial Evaluates Efficacy and Safety of TRK Inhibitor Larotrectinib
Frequency of NTRK Fusions in Gastrointestinal Stromal Tumors
Enhancing the Diagnostic Accuracy of Secretory Carcinoma of the Salivary Gland
Clinical Outcomes With Larotrectinib in Patients Who Have TRK Fusion–Positive Thyroid Cancer
How Often Are Oncologists Testing for NTRK Gene Fusion and Using Results to Modify Treatment?
Brain Metastasis Model of NTRK-Rearranged Tumors: Focus on Treatment Resistance
RET/NTRK Fusions and Risk of Metastasis in Pediatric Differentiated Thyroid Cancer
NTRK Gene Fusions in Undifferentiated Sarcomas in Pediatric Patients
Age-Dependent Biologic Consequences of NTRK and RET Gene Fusions in Thyroid Cancer
TRK Mutations: How to Find Them and Target Therapy for Select Solid Tumors
Rapid Multiplex RNA-Based Assay Under Study in Detection of Genetic Rearrangements and Alterations
Is Pan-TRK Immunohistochemistry the Optimal Way to Identify NTRK Gene Fusions in Brain Tumors?
Researchers Identify Key Regulator of NTRK Fusion Pathway Activation in Thyroid Cancer
Screening for NTRK Fusions in Glioblastomas: FISH Versus IHC
Use of TRK Inhibitors in Pediatric Patients With Cancers Harboring NTRK Fusions
Examining the Influence of NTRK Gene Fusions in Solid Tumors
Rare Case of TPM3-NTRK Rearrangement in Recurrent Ovarian Cancer
Long-Term Update on Entrectinib for NTRK Fusion–Positive Solid Tumors
Novel Therapeutics for NTRK Fusion–Positive Infantile Fibrosarcoma
Histologic Characterization of an NTRK-Rearranged Spindle Cell Neoplasm: Case Report
Identifying Actionable Gene Fusions Using a Functional Genomic Approach
Genetic Alterations in Inflammatory Myofibroblastic Tumors
Next-Generation Sequencing Guides Treatment in Spinal Cord Tumor With NTRK Fusion: Case Report
Response to Immunotherapy in NSCLC: Beyond EGFR Mutations
Singapore Task Force: When and How to Test for NTRK Gene Fusions in Select Cancers
Cytomorphologic Features of NTRK-Mutated Papillary Thyroid Cancer
First- Versus Second-Generation TRK Inhibitors for NTRK Fusion–Positive Cancers
Next-Generation ROS1/TRK/ALK Inhibitor Under Study in Neuroblastoma
Are NTRK Fusions ‘Bona Fide’ Oncogenic Drivers of Lung Cancer?
Use of Larotrectinib for in Sarcoma of the Chest: Case Study Focused on TMTC2-NTRK3 Fusion
Lipofibromatosis-Like Neural Tumor: Case Featuring an NTRK Abnormality
Case Study: Broad Morphologic Spectrum of Mesenchymal Tumors With NTRK Fusions
Serrated Neoplasia Pathway: A Clue to NTRK-Rearranged Colorectal Tumors
Case Report: Use of FISH Signal Pattern to Confirm Secretory Carcinoma of the Salivary Gland
Pediatric Thyroid Cancer: Should Molecular Subtype Be Included in Risk Stratification?
Multitargeted Treatment Approach to Mammary Analog Secretory Carcinoma: Case Report Focuses on NTRK Fusions
Gene Fusion Testing Strategies for Colorectal, Skin, and Lung Cancers
Larotrectinib for TRK Fusion–Positive Gastrointestinal Cancer
Can NTRK Gene Fusions Influence Chromosomal Imbalances in Soft-Tissue Sarcomas?
TRK Inhibitors for NTRK Fusion–Positive Sarcoma: A Canadian Perspective
Targeting NTRK Gene Fusions in Gliomas
NTRK1-TPM3 Gene Rearrangement in Recurrent Ovarian Cancer: Case Report
How Common Are NTRK Fusions in Bone Tumors in Pediatric Patients?
Rare Case of Mesenchymal Sarcoma With NTRK1 Gene Translocation
European Pediatric Sequencing Programs: Screening for Targetable NTRK Gene Fusions
Differentiated Thyroid Cancer: Molecular Profiling for NTRK Gene Fusions in Assessing Risk for Recurrence
NTRK3 Promoter Methylation: Predictive Marker for Survival in Colorectal Cancer?
Rare Case of Mosaicism in a Glioblastoma Harboring NTRK Fusion and PDGFRA Amplification
Larotrectinib for Pediatric Undifferentiated Sarcoma With an STRN-NTRK2 Fusion: Case Study
Larotrectinib in RAI-Refractory Papillary Thyroid Cancer: Case Report
NTRK Fusion–Positive Solid Tumors: Entrectinib Granted Conditional Marketing Authorization in the European Union
Can Pan-TRK Immunohistochemistry Identify NTRK Fusions in Lung Cancer?
Case Report: Use of Larotrectinib in a Boy With TRK Fusion–Positive ALL
NTRK Fusions and Cancer: Focus on Biology and Therapeutic Targeting of These Drivers
Shedding Light on the Landscape of NTRK Aberrations in Pediatric and Adult Tumors
Novel TFG‐NTRK2 Fusion in Spitz/Reed Tumor: Case Report
Entrectinib in NTRK Fusion– and ROS1 Fusion–Positive Solid Tumors: Patient-Reported Outcomes
Identifying NTRK Gene Fusions for Targeted Therapy: ‘An Ongoing Clinical Priority’
Larotrectinib for Advanced Lung Cancer With Novel NCOR2-NTRK1 Fusion: Case Study
Study Identifies Benefits of Testing for NTRK Fusions in Thyroid Cancers
Understanding NTRK Fusion Actionability: An Overview of Targeted Therapy Options
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