Mark J. Levis, MD, PhD, on AML: First-in-Human Study of an FLT3 Inhibitor

Posted: Monday, June 7, 2021

Mark J. Levis, MD, PhD, of the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, discusses phase I data on a FF-10101-01 FLT3 inhibitor, which has shown activity in patients with refractory or relapsed acute myeloid leukemia, including those with mutations resistant to gilteritinib and other FLT3 kinase inhibitors. The study may be an important first step in targeting a mutation associated with high relapse and low survival and remission rates.

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