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AACR II: Race-Based Survival Differences in Patients With AML Living in Texas

By: Joshua D. Madera, MS
Posted: Thursday, June 25, 2020

Hispanic patients with acute myeloid leukemia (AML) who are living along the United States/Mexico border in El Paso, Texas, seem to have a worse overall survival compared with Hispanic patients with AML diagnosed in other parts of Texas, according to a retrospective analysis presented at the American Association for Cancer Research Virtual Annual Meeting II (Abstract 4343/7). In addition, these study findings from the Texas Cancer Registry for hematologic malignancies showed a surprisingly better overall survival in Hispanic patients with AML, myelodysplastic syndromes, and chronic myeloid leukemia (CML) compared with non-Hispanic white patients.

“Hispanic individuals living at the border tend to be poorer, are more likely to lack health insurance, and many could be undocumented,” explained lead study author Alfonso Bencomo-Alvarez, PhD, of Texas Tech University Health Sciences Center, El Paso, in an AACR press release. “These factors could discourage individuals from visiting a physician and may therefore affect health outcomes in those residing at the border.”

From 1995 to 2016, data on 69,941 Hispanic and non-Hispanic white patients with hematologic malignancies were collected from the Texas Cancer Registry. To understand how living near the United States/Mexico border might impact survival, the investigators focused on 1,160 Hispanic patients residing in El Paso, Texas, and 9,662 Hispanic patients living in other parts of the state.

The investigators reported that Hispanic patients were younger at the time of diagnosis compared with non-Hispanic white patients. In addition, Hispanic patients with AML living near the United States/Mexico border had significantly lower 10-year survival rates than patients living in other areas of the state (13% vs. 22%). Worse 10-year survival rates were also seen in Hispanic patients with acute lymphoblastic leukemia and CML living in El Paso than in patients living elsewhere in Texas.

Disclosure: The study authors reported no conflicts of interest.



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